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College of Health Sciences, LAUTECH, Ogbomoso, Oyo State
Verification Status
Admin:  
Pending
HR:  
Pending
Dr. Kolawole Oyetunji Timothy
Senior Lecturer
Male
Faculty: Faculty of Basic Clinical Sciences
Department: Department of Pharmacology
Directorate/Unit:

Brief about me

For many years, I have taught Medical, Nursing, and Medical Laboratory students at undergraduate and postgraduate levels. I have also supervised the research projects of many students. Currently, I am supervising two undergraduate students from the Department of Medical Laboratory Science. In the area of research, I have established the therapeutic efficacy of the leaves of Newbouldia laevis in diabetes mellitus through its interaction with glucose metabolizing enzymes. My research has also shown that extracts from the leaves of Newbouldia laevis possess anticonvulsant and antipsychotic properties. My current research is centered on screening medicinal plants for antidiabetic, anticonvulsant, sedative, anxiolytic, analgesic, anti-inflammatory, and other biological activities. It also involves toxicological evaluation of drugs, food additives, and natural products with bioactive components.

 

Academic Qualifications
PhD. Pharmacology 2021
MSc. Pharmacology 2004
BSc. Pharmacology 1995

Professional Qualifications

Skills
Ability to lead and conduct pharmacological and toxicological research
Data Analysis
Handling of laboratory animals
Extraction procedures for medicinal plants

Interests
Screening medicinal plants for antidiabetic, anticonvulsant, sedative, anxiolytic, analgesic, anti-inflammatory, and other biological activities
Toxicological evaluation of drugs, food additives, and natural products with bioactive components

Languages
English
Yoruba

List of Publications

1. Olajide, O.A., Akinola Alada, A.R., Kolawole, O.T. (2005). Anti-inflammatory properties of Entada abyssinica leaves Pharmaceutical Biology 43(7): 583-585

2. Olajide, O.A., Kolawole, O.T., Fagbohun, T.R., Ajayi, F.F. (2005). Evaluation of anti-inflammatory properties of Chlorophora excelsa bark extract. Pharmaceutical Biology 43(9): 746-748.

3. Kolawole, O.T., Makinde, J.M., Olajide, O.A. (2007). Central nervous system depressant activity of Russelia equisetiformis. Nigerian Journal of Physiological Sciences 22 (1-2): 59-63. 

4. Kolawole, O.T., Kolawole, S.O. (2010). Effects of Russelia equisetiformis methanol and aqueous extracts on hepatic function indices. Biology and Medicine 2(3): 38-41

5. Kolawole, S.O., Kolawole, O.T., Akanji, M.A. (2011). Effect of aqueous extract of Khaya senegalensis stem bark on biochemical and hematological parameters in rats. Journal of Pharmacology and Toxicology 6(6): 602-607

6. Kolawole, O.T., Abiona, F.E., Kolawole, S.O., Ayankunle, A.A., Olaniran, O.I. (2011). Effect of Momordica charantia fruit extract on normal and alloxan-diabetic rats. International Journal of Pharmacology 7(4): 532-535

7. Kolawole, O. T., Akiibinu, M. O., Ayankunle, A. A. (2012). Anticonvulsant and depressant activity of methanol leaf extract of Croton zambesicus. International Journal of Tropical Disease and Health. 2(1): 33-41

8. Ayankunle A.A., Kolawole, O.T., Adesokan, A.A., Akiibinu, M.O. (2012). Antibacterial activity and sub-chronic toxicity studies of Vitellaria paradoxa stem back extract. Journal of Pharmacology and Toxicology 7(6): 298-304

9. Kolawole, O.T., Kolawole, S.O., Ayankunle A.A., Olaniran, O.I. (2012). Anti-hyperglycemic effect of Khaya senegalensis stem bark aqueous extract in Wistar rats.  European Journal of Medicinal Plants 2(1): 66-73

10. Kolawole, O.T., Kolawole, S.O., Ayankunle, A.A., Olaniran, I.O. (2012). Methanol leaf extract of Persea Americana protects rats against cholesterol-induced hyperlipidemia. British Journal of Medicine and Medical Research 2(2): 235-242

11. Kolawole, O.T., Ayankunle, A.A. (2012). Seasonal variation in the anti-diabetic and hypolipidemic effects of Momordica charantia fruit extract in rats. European Journal of 

Medicinal Plants 2(2): 117-185

12. Kolawole, O.T., Akanji, M.A. (2013). Inhibitory effect of leaf extract of Newbouldia laevis on the metabolic activities of α-glucosidase and α-amylase. Bangladesh Journal of Pharmacology. 8: 371-377

13. Kolawole, O.T., Akanji, M.A., Awe, O.E., Akiibinu, M.O. (2013). Ethanolic extract of leaves of Newbouldia laevis attenuates glycosylation of hemoglobin and lipid peroxidation in diabetic rats. American Journal of Pharmacology and Toxicology 8(4): 179-186

14. Kolawole, O.T., Akiibinu, M.O., Ayankunle, A.A., Awe, E.O. (2013). Evaluation of antiinflammatory and antinociceptive potentials of Khaya senegalensis A. Juss  (Meliaceae) stem bark aqueous extract. British Journal of Medicine and Medical Research 3(2): 216-229 

15. Kolawole, O.T., Akanji, M.A., Akiibinu, M.O. (2013). Toxicological assessment of ethanolic extract of the leaves of Newbouldia laevis (P. Beauv). American Journal of Medicine and Medical Sciences 3(4): 74-80

16. Awe, E.O., Kolawole, O.T. (2013). Biochemical, haematological and histopatholo-gical  assessment of toxic effects of Manihot esculenta Crantz leaf aqueous extract in rats. International Journal of Pharma and Bio Sciences 4(3): 228-235

17. Wakeel O.K, Umukoro S, Kolawole O.T, Awe E.O, Ademowo O.G. (2014). Anticonvulsant and Sedative activities of extract of Erythrophleum ivorense stem bark in mice. Asian Journal of Biomedical and Pharmaceutical Sciences 4(2): 44-47

18. Kolawole, O.T., Akanji, M.A. (2014). Anti-inflammatory and antioxidant activities of ethanolic extract of leaves of Newbouldia laevis in diabetic rats Canadian Journal of Pure and Applied Sciences 8(2): 2851-2857

19. Kolawole, O.T., Akanji, M.A. (2014). Protective effect of Newbouldia laevis leaf extract against dyslipidemia and hepatorenal dysfunction in diabetic rats. International Journal of Pharma and Bio Sciences 5(1): 646-655

20. Kolawole, O.T., Akanji, M.A. (2014). Effects of extract of leaves of Newbouldia laevis on the activities of some enzymes of hepatic glucose metabolism in diabetic rats. African Journal of Biotechnology 13(22): 2273-2281

21. Akiibinu, M.O., Kolawole, O.T. (2014). Markers of oxidative stress and C-reactive protein levels in asthmatics. Journal of Medicine and Medical Sciences 5(4): 93-96

22. Akiibinu, M. O., Kolawole, T.O., Ekun, O. A., Akiibinu, S. O. (2015) Metabolic dysfunctions in Nigerian Pre-eclamptics. Archives of Gynecology and Obstetrics. 288(5): 1021- 1026

23. Wakeel O.K, Ayankunle A.A., Olapade M.K., Kolawole O.T., and Oyekale A.O (2018). Anxiolytic-like effect of crude methanol extract of Erythrophleum ivorense in mice. European Journal of Biomedical and Pharmaceutical sciences 5(6): 29-35

24. Ayankunle, A.A., Wakeel, O.K., Kolawole, O.T., Ojurongbe, O., Adeyeba, O.A.  (2019). Chemo-suppressive activities of clotrimazole and gabapentin in a murine malarial model. World Journal of Pharmacy and Pharmaceutical Sciences 8(5): 72-82

25. Wakeel, O.K., Adebayo-Mogaji, R.A., Awosan, B.O., Olatoyan-Layonu, T.J., Olapade, M.K, Kolawole, O.T., Adeyeba, O.A. (2020). Antinociceptive potential of methanol extracts of Cranium jagus (J. Thomps) in mice. European Journal of Biomedical and Pharmaceuticl Sciences 7(10): 43-50 

26. Kolawole O.T, Adeyeba O.A, Awodele O, Wakeel O.K, Ayankunle A.A (2020). Crude and partitioned extracts of Newbouldia laevis leaves attenuate excitotoxin-induced stereotypy in mice. European Journal of Medicinal Plants 31(18): 29-36

27. Wakeel O.K, Awosan O.B, Kolawole O.T, Ayankunle A.A, Onaolapo O.J, Adeyaba O.A. (2020). Potential mechanisms involved in the anticonvulsant effect of methanol extract of Pyrenancantha staudtii in mice. Central Nervous System Agents in Medicinal Chemistry 20(2): 144-154

28. Ayankunle A.A, Wakeel O.K, Kolawole O.T, Oyekale A.O, Ojurongbe O, Adeyeba O.A (2020). Drug repositioning: Antimalarial activities of analogs of GABA in mice infected with Plasmodium berghei. Central Nervous System Agents in Medicinal Chemistry 20(2): 110-121

29. Wakeel O.K, Ayankunle A.A, Oluogun W.A, Kolawole O.T, Adeyeba O.A (2020). Protective effect of methanol extract of Russelia equisetiformis against paracetamol-induced hepatotoxicity in Wistar rats. Universal Journal of Pharmaceutical Research 5(6): 24-28

30. Kolawole O.T, Adeyeba O.A, Awodele O, Wakeel O.K, Ayankunle A.A (2021). Protective effect of crude extract and fractions of Newbouldia laevis leaves in chemoconvulsant-induced seizures. Tropical Journal of Natural Product Research 5(1): 217-224